Our Mission

Our Mission

Empowering Healthier, Longer Lives Through Innovation

Empowering Healthier, Longer Lives Through Innovation

Our vision is to transform how we treat age-related diseases — not by targeting isolated symptoms, but by addressing the underlying biology that drives them.

Refoxy’s discovery platform focuses on FOXO3, a transcription factor that orchestrates the body’s natural defense mechanisms against stress, damage, and aging. By developing small molecules that selectively activate FOXO3, we aim to restore balance across multiple systems, with the potential to treat fibrosis, cardiovascular diseases, and other conditions.

To support this work, we have developed a proprietary discovery platform called F.act finder (FOXO Activator Finder), which helps us identify, validate, and optimize compounds with a focus on precision, safety, and therapeutic relevance.

a close up of a plastic model of a human brain
a close-up of a white circle

Focus on the real problem

Focus on the real problem

Driving Innovation to Combat Age-Related Diseases

For the first time in human history, there are more 65-year-olds than 5-year-olds. This highlights an unpresedented societal problem, as aging is the biggest risk factor for the development of complex diseases, and our goal is to tackle its root causes.

For the first time in human history, there are more 65-year-olds than 5-year-olds. This highlights an unpresedented societal problem, as aging is the biggest risk factor for the development of complex diseases, and our goal is to tackle its root causes.

For the first time in human history, there are more 65-year-olds than 5-year-olds. This highlights an unpresedented societal problem, as aging is the biggest risk factor for the development of complex diseases, and our goal is to tackle its root causes.

man and woman sitting on bench facing sea
man and woman sitting on bench facing sea
man and woman sitting on bench facing sea

Around 95% of adults aged 60

Around 95% of adults aged 60

and older have at least one chronic age-related condition, and nearly 80% have two or more

and older have at least one chronic age-related condition, and nearly 80% have two or more

Fibrotic diseases account for approximately 35% of all deaths worldwide.

Fibrotic diseases account for approximately 35% of all deaths worldwide.

By 2050, the global population aged 65+ is expected to double, increasing the demand for longevity-focused treatments

By 2050, the global population aged 65+ is expected to double, increasing the demand for longevity-focused treatments

Our Path Forward

Our Path Forward

Cultivating values and a company culture to enable breaktrhough discoveries

Scientific Excellence

We are committed to rigorous research and cutting-edge innovation, ensuring our therapies meet the highest scientific and medical standards.

Integrity & Transparency

We embrace bold ideas and pioneering approaches to unlock new possibilities in longevity and age-related disease treatment.

Patient-Centered Impact

Every discovery we make is driven by the goal of improving lives. We prioritize patient well-being in all aspects of our work.

Backed by

Backed by

We’re proud to be backed by a strong syndicate of mission-aligned investors and scientific advisors who believe in the potential of FOXO3-based therapeutics to change lives.

We’re proud to be backed by a strong syndicate of mission-aligned investors and scientific advisors who believe in the potential of FOXO3-based therapeutics to change lives.

Discover How Advanced Science Can Transform Health

Get in touch

Discover How Advanced Science Can Transform Health

Get in touch

Contact

info@refoxy.com

Refoxy Pharmaceuticals GmbH

c/o Startplatz I Im Mediapark 5 I 50670 Cologne I Germany

All Rights Reserved Refoxy Pharmaceuticals GmbH

Contact

info@refoxy.com

Refoxy Pharmaceuticals GmbH

c/o Startplatz I Im Mediapark 5 I 50670 Cologne I Germany

All Rights Reserved Refoxy Pharmaceuticals GmbH

Contact

info@refoxy.com

Refoxy Pharmaceuticals GmbH

c/o Startplatz I Im Mediapark 5 I 50670 Cologne I Germany

All Rights Reserved Refoxy Pharmaceuticals GmbH